Inferring functional units in ion channel pores via relative entropy
نویسندگان
چکیده
منابع مشابه
Biophysics, pathophysiology, and pharmacology of ion channel gating pores
Voltage sensor domains (VSDs) are a feature of voltage gated ion channels (VGICs) and voltage sensitive proteins. They are composed of four transmembrane (TM) segments (S1-S4). Currents leaking through VSDs are called omega or gating pore currents. Gating pores are caused by mutations of the highly conserved positively charged amino acids in the S4 segment that disrupt interactions between the ...
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ژورنال
عنوان ژورنال: European Biophysics Journal
سال: 2021
ISSN: 0175-7571,1432-1017
DOI: 10.1007/s00249-020-01480-7